Research

The human immune system is a complex network of cells, tissues, and signaling molecules that serves as a defense system. It continuously identifies and eliminates viruses, bacteria, abnormal cells, an

Public attention to nicotinamide mononucleotide has grown quickly as evidence about NAD+ biology has entered mainstream discussion. Early animal data suggested broad benefits across metabolic and vasc

For patients living with blood cancer or a severe blood disorder, a stem cell transplant is often the turning point between decline and recovery. Yet for years in the UK, the calendar has been the ene

Chronic illness drives demand across the NHS and shapes budgets, workforce planning and service design. People living with multiple long-term conditions account for around half of hospital admissions,

Calciphylaxis, also termed calcific uremic arteriolopathy, is uncommon yet catastrophic. Small and medium dermal arterioles mineralise and thrombose, tissue perfusion collapses, and exquisitely painfu

The idea that a single infusion of a patient's own immune cells could clear aggressive cancer once seemed like daring fiction. CAR T‑cell therapy has turned that notion into clinical fact, standing sh

Cellular ageing is not a single event but a convergence of gradual molecular failures that accumulate over time. The recognised hallmarks include telomere attrition, genomic instability from DNA damag

Gene therapy is moving from specialist promise to established practice in 2025. Approvals have broadened across indications, clinical data in Huntington's disease have shifted expectations for neurolo

Human gene editing sits at a pivotal point in modern medicine. Its capacity to change DNA with precision has moved from conjecture to clinical practice, raising hopes for curative treatments while ign

Huntington's disease remains without a cure in 2025. Clinical practice focuses on symptom control while a new wave of molecular programmes seeks to slow or halt neurodegeneration. The evidence base po

For acute pain, time matters. Patients with postoperative dental pain, primary dysmenorrhoea, tension-type headache or migraine want relief that begins quickly and remains reliable. Ibuprofen lysine,

Five years after the acute waves of COVID-19, Long COVID has settled into public health planning as a common post-infectious condition with sustained clinical, economic and social effects. The term de